Late Breaking

AARON PRYOR JR. SCORES SIXTH ROUND STOPPAGE OVER WILLIS LOCKETT TO HIGHLIGHT AN EXCITING AFTERNOON OF BOXING

PHILADELPHIA (June 13, 2010)—On Sunday it was a special afternoon of boxing as Aaron Pryor Jr. highlighted a four bout card with a sixth round stoppage over gritty Willis Lockett at the Hyatt Regency on the Philadelphia Waterfront.

The show was promoted by Joey Eye Boxing in association with Gulfstream Sports and Entertainment.

Pryor Jr. of Cincinnati used his six inch height advantage to keep Lockett at range but Lockett was able to get through with some winging shots over the first three rounds. Pryor Jr. got things rolling in round four as he began to find the range with his right hand startled Lockett on several occasions.

Lockett started to hold and was deducted a point for that continued infraction by referee Benjy Esteves in round six as he began to eat more hard shots.

The accumulation of punches had taken their toll on Lockett and his corner agreed as they stopped the bout before the seventh round had started.

In a entertaining brawl, Julio Cesar Matthews escaped with a razor thin unanimous decision over tough Philadelphia banger, Garrett Wilson in a six round Cruiserweight bout.

Matthews controlled the action over the first part of the fight as he bloodied the nose and mouth of Wilson. Wilson started to come on like gangbusters and if the fight was scheduled for more rounds, there is no telling what the outcome would have been as Matthews with stood a late onslaught of Wilson.

Andreas Gustaffson of Sweden took out Pedro Martinez in round two of a scheduled six round Heavyweight bout. Gustafsson dropped Martinez from a good looking counter left. Later in the round, Gustafsson landed a nice four punch combination that was capped off by a right hand that sent Martinez to the canvas and the fight was called off at 1:05 of round two.

In the opening bout, Kamarah Pasley scored an upset as he scored a first round knockdown en route to a four round unanimous decision over previously undefeated Patrick Farrell in a cruiserweight bout.

Pasley dropped Farrell in round one from a counter left. Farrell started pressing the action in round’s two and three but Pasley had a solid round four as he continuously created space and was efficient with some solid left uppercuts.

FULL RESULTS

8 Rounds Super Middleweights—Aaron Pryor Jr. (13-2, 11 KO’s) 166 lbs of Cincinnati, OH (13-2, 11 KO’s) TKO END OF 6 over Willis Lockett (12-10-5)162 ½ lbs of Takoma Park, MD

6 Rounds Cruiserweights—Julio Cesar Matthews (10-0) 185 ½ lbs of Reading, PA U DEC (58-55, 57-56 & 57-56) over Garrett Wilson (7-5) 190 lbs of Philadelphia, PA

6 Rounds Heavyweights—Andreas Gustafsson (5-0, 3 KO’s) 234 lbs of Norkopping, Sweden TKO 2 (1:05) over Pedro Martinez (5-3) 233 lbs of Philadelphia, PA

4 Rounds Cruiserweights – Kamarah Pasley (5-4) 198 lbs of Philadelphia U DEC (39-36, 38-37 & 38-37) over Patrick Farrell (5-1) 198 ½ lbs of Jersey City, NJ

Langerhans cell histiocytosis: Multifocal eosinophilic granuloma – a case report.(Musculoskeletal)(Clinical report)

Indian Journal of Radiology and Imaging January 1, 2006 | Nagendra, Hvk; Hegde, K.

Byline: HVK. Nagendra, K. Hegde INTRODUCTION Localised langerhans cell histiocytosis of bone (eosinophilic granuloma) is a benign tumor like condition with a variable clinical course [1]. Peak incidence is between the ages of 5 and 10 yrs and 75% of cases occur in persons under 20 years of age [2]. We present a case of langerhans cell histiocytosis: multifocal eosinophilic granuloma of skull bone with typical radiologic features.

CASE REPORT A six years old girl presented with swelling over the right parietal region. There was no history of fever or trauma. On clinical examination there was minimal tenderness over the swelling. The patient was later subjected to radiological and hematological examinations. Hematologic investigations were within normal limits. site langerhans cell histiocytosis

Anteroposterior and lateral skull radiographs showed multiple lytic lesions on the parasagittal region of the right parietal bone and at fronto-temporal suture line of the right frontal bone [Figure 1][Figure 2].

Axial CT sections of the cranium showed osteolytic lesion in the high parietal bone in its posterior aspect on the right side, measuring 4.3cm in width with a small intact bony fragment in the centre (button sequestrum). Inner and outer table of the skull were eroded [Figure 3],[Figure 4]. Another osteolytic lesion measuring 1.4 cm in width was noted in the frontal bone on right side at fronto-temporal suture line [Figure 5].

Chest radiograph posteroanterior view showed no abnormality. Ultrasonography of abdomen was normal.

The radiological features were suggestive of langerhans cell histiocytosis: multifocal eosinophilic granuloma.

DISCUSSION Langerhans cell histiocytoses are a group of seemingly diverse diseases all characterized by the abnormal accumulation of inflammatory histiocytes. The severity of manifestations and the duration of illness in histiocytoses vary from benign and self-limited to acute, disseminated and fatal. Eosinophilic granuloma was first described by Jaffe and Lichtenstein in 1944 [3]. Lichtenstein observed the similarities between eosinophilic granuloma, Hand-Schuller-Christian disease and Litterer-Siwe disease and proposed that they be considered as variants of a single process collectively known as “Histiocytosis ‘x’ [4] also known as Langerhans cell histiocytosis.

Eosinophilic granuloma accounts for upto 60% of all cases of langerhans cell histiocytosis and most frequently affects the skeleton in a monostotic or polyostotic fashion with the solitary lesions prevailing by more than three to one over multiple lesions. Any bone can be involved, but more than 50% of lesions occur in the skull, spine, pelvis, ribs and mandible [2]. Presence of proliferating histiocytes is the histologic hallmark of langerhans cell histiocytosis, including eosinophilic granuloma. Morphologically these disorders are characterized by proliferation of mononuclear and sometimes multinucleated cells with pale, ill defined eosinophilic cytoplasm and lobulated nuclei with longitudinal grooves. Electron microscopy used for definitive diagnosis shows distinctive structures called langerhans or Birbeck granules. These are rod like structures, with a striated core that may have a dilated end, giving them a tennis racket appearance. The Birbeck granules are organelles seen singly or in small clusters in the cytoplasm or as invagination of the plasma membrane and they are believed to be products of internalization of complexes derived from antigen at the cell membrane Expression of CD1a by immunohistochemistry is also considered diagnostic of Langerhans cell histiocytosis [2],[5]. in our site langerhans cell histiocytosis

The radiological features vary considerably depending on the site of the lesion. In the skull round to oval osteolytic lesion about 1-4 cm in diameter is seen. More than one lesion may be present. The lesion tends to have sharp borders with a punched out appearance. Involvement of both the inner and outer tables results in a double-contour or bevelled edge appearance. The lesion usually causes asymmetric bevelling which can be palpated beneath the scalp. At times a button sequestrum may be present within the osteolytic lesion, representing residual bone. The sequestrum may be seen better on CT scans [2],[4], and is considered to be diagnostic hallmark of eosinophilic granuloma.

Radiographic findings of eosinophilic grannuloma in skull resemble venous lakes, arachnoid granulations, persistently enlarged parietal foramina (especially when unilateral). Epidermoid cysts or haemangiomas may produce lesions resembling eosinophilic granuloma in the skull [2].

References 1. Plasschaert F, Craig C, Bell R, Cole WG, Wuner JS, Alman BA. Eosinophilic Granuloma: A Different Behaviour In Children Than In Adults. J Bone Joint Surg [Br] 2002; 84 (6): 870-872.

2. David R, Oria RA, Kumar R, et al. Radiologic features of eosinophilic granuloma of bone. AJR, 1989; 153: 1021.

3. Jaffe HL, Lichtenstein L. Eosinophilic Granuloma of Bone. Arch Pathol, 1944; 37: 99.

4. Smirniotopoulos JG, Olmsted WW. Primary and Secondary Neoplasms of the Skull. In: Putman CE, Ravin CE, eds. Textbook of Diagnostic Imaging, 2nd ed, Philadelphia: WB Saunders, 1994: 118.

5. Borrego O, Barness EG. Eosinophilic Granuloma (Langerhans Histiocytosis). Arch Pediatr Adolesc Med. 1998; 152: 91-92.

Nagendra, Hvk; Hegde, K.